Low-level impulse lasers have been applied focally to stimulate acupoints (laser acupuncture) and topically over wounds, joints and other tissues to increase circulation and promote healing. Laser acupuncture has been used to treat neck and back pain, tendonitis, osteoarthritis, injuries, chronic allergies, immune-mediated disorders, internal medical disorders and other diseases. Low level impulse laser therapy (LLLT) reduces inflammation and muscle spasms, increases blood perfusion and encourages clearance of peroxide radicals and healing in abscessed and degenerating tissues. Twenty one horses with laminitis were presented to the author for LLLT on acupoints and topically to encourage microcirculation and demarcation of abscesses of the hoof. Before and after completion of a series of LLLT treatments, each horse was evaluated and given a pain score based on a pre-determine pain scale. The mean ± standard deviation of pre- and posttreatment pain scores were compared with a t-test and were significantly different at p<0.001. Photographs of severe cases of laminitis in horses recommended for euthanasia are shown before and after LLLT. The results of this pilot study support the use of LLLT as a primary or adjunctive treatment option for equine laminitis and indicate the need for further exploration of LLLT for laminitis and other diseases in animals.