The effect of adding Liver-3 (LIV-3) acupuncture point on isoflurane anesthetic usage during orchiectomy surgery was evaluated in a controlled, randomized, blinded study using 32 intact male dogs. The dogs were divided into 2 groups (16 Control Group dogs, 16 Test Group dogs). The control group underwent anesthetic induction followed by maintenance on isoflurane gas using a regular anesthetic protocol. The test group used a regular anesthetic protocol but in addition, acupuncture needles were inserted bilaterally at LIV-3 after the dog was placed in the surgical suite. A technician blinded to treatment group monitored isoflurane (% concentration) anesthetic use needed to maintain a good surgical plane of anesthesia (Stage 3, Plane 2). The initial isoflurane concentration (2%) was compared to actual anesthetic requirement during surgery for both groups. The use of LIV-3 during surgery in test group dogs resulted in a 93.7% reduction of anesthetic (1.37% ±0.08) while demanded anesthetic in the control group remained at 2% (2.01 ± 0.05). Comparison of anesthetic use between the 2 groups yielded a statistically significant reduction (p = 4.30 x 10^-6) of isoflurane usage by test group dogs of 32%. Study results concluded that the addition of acupuncture needles at LIV-3 enhanced the efficiency of maintaining a good plane of anesthesia with resultant use of less gas anesthetic and stabilized blood pressure during the surgical procedure. The results of this study benefit the veterinary clinician using integrative medicine by providing evidence-based results on the benefits of adding this low cost simple procedure during surgery.