Liu Wei Di Huang Wan (Six-Ingredient Pill with Rehmannia) is considered the most famous basic tonic herbal formula to treat Kidney and Liver Yin Deficiency. The Yin of the Kidney and Liver is often referred to as the base or true Yin for the entire body.1 The original source of Liu Wei Di Huang Wan is from Xiao Er Yao Zheng Zhi Jue (Craft of Medicinal Treatment for Childhood Disease Patterns) by Qian Yi written in 1119. It is known by several alternate names, two of the most common being Six-Flavor Rehmannia Pill and Rehmannia Six Pills. Liu Wei Di Huang Wan is composed of six (liu) different herbs, three tonic and three sedative. Shu Di Huang (Radix Rehmanniae Praeparata), the chief herb, tonifies Kidney Yin and Jing (Essence), and fills the marrow. Shan Zhu Yu (Fructus Corni) nourishes the Liver and Kidney and astringes Jing. Shan Yao (Rhizoma Dioscoreae) tonifies the Spleen and Kidney and consolidates Jing. Together, these three tonic herbs address deficiencies in the Kidney, Liver, and Spleen. Ze Xie (Rhizoma Alismatis) sedates the Kidney, causes turbidity to descend, and controls the stagnating effect of Shu Di Huang. Mu Dan Pi (Cortex Moutan) sedates Deficiency Fire of the Liver, as well as balances the astringent property of Shan Zhu Yu. Fu Ling (Poria) strengthens the Spleen, resolves dampness, and balances Shan Yao.