A 1.5-year-old spayed female French Bulldog and Pitbull mix was presented for a Traditional Chinese Veterinary Medicine (TCVM) consultation due to chronic skin disease unresponsive to conventional therapies. The dog exhibited severe pruritus, dermatitis, alopecia, otitis externa, and self-mutilation. Initial diagnostic workup confirmed Demodex canis infestation and secondary bacterial and yeast infections. A TCVM diagnosis of Kidney Jing Deficiency, Kidney Yin Deficiency, and Blood Deficiency with localized Damp-Heat was established. Integrative treatment included acupuncture, Chinese herbal medicine, food therapy, and conventional interventions such as antibiotics and ivermectin. The patient showed rapid and sustained improvement, highlighting the effectiveness of a multimodal treatment approach. This case underscores the importance of integrating TCVM and Western medicine for chronic dermatological conditions, particularly in cases where conventional therapy alone has failed.